Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13534726 | 1.00 | CYP2D6 (0.47) | CYP2D6BACE1OPRL1TDP1PSEN1 | |
| SCHEMBL6075390 | 1.00 | CYP2D6 (0.47) | CYP2D6BACE1OPRL1TDP1PSEN1 | |
| SCHEMBL10510512 | 1.00 | CYP2D6 (0.47) | CYP2D6BACE1OPRL1TDP1PSEN1 | |
| SCHEMBL10507152 | 0.88 | PPARG (0.39) | CYP2D6BACE1OPRL1MAPT | |
| SCHEMBL13534746 | 0.88 | ALDH1A1 (0.38) | CYP2D6BACE1OPRL1ALDH1A1ALOX15 | |
| SCHEMBL13534719 | 0.87 | OPRL1 (0.42) | CYP2D6OPRL1 | |
| SCHEMBL13537106 | 0.86 | CYP2D6 (0.37) | CYP2D6BACE1OPRL1TDP1ALDH1A1 | |
| SCHEMBL13534736 | 0.86 | SPR (0.39) | CYP2D6OPRL1TDP1 | |
| SCHEMBL13534732 | 0.86 | SMN1; SMN2 (0.40) | CYP2D6OPRL1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL13534728 | 0.85 | KDM4E (0.38) | CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307184-B2 | Processes for preparing oxazolidinone derivatives of β-hydroxyethlamine compounds and for preparing β-hydroxyethlamine compounds | KANEKA CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-20060135784-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXYPROPIONIC ACID DERIVATIVES | KANEKA CORPORATION | 2006-06-22 | — | — | US | disclosed |
| US-7057066-B2 | Process for producing 3-amino-2-hydroxypropionic acid derivatives | KANEKA CORPORATION (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20040181074-A1 | Process for producing oxazolidinone derivative of beta-hydroxyethylamine compound and for producing beta-hydroxyethlamine compound | KANEKA CORPORATION (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1403257-A1 | PROCESSES FOR PRODUCING OXAZOLIDINONE DERIVATIVE OF BETA-HYDROXYETHYLAMINE COMPOUND AND FOR PRODUCING BETA-HYDROXYETHYLAMINE COMPOUND | KANEKA CORPORATION (JP) | 2004-03-31 | — | — | EP | disclosed |
| EP-1300391-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXYPROPIONIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2003-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135784-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXYPROPIONIC ACID DERIVATIVES | AASDHPPT, HPD, HAAO | CYP2D6 409/4885BACE1 1315/4885OPRL1 1163/4885 |
| US-20040181074-A1 | Process for producing oxazolidinone derivative of beta-hydroxyethylamine compound and for producing beta-hydroxyethlamine compound | HNMT, PNMT, HRH4 | CYP2D6 267/4885BACE1 1128/4885OPRL1 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.