Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.41 |
| ▸ | ATP4B | P51164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569582 | 0.81 | HSF1 (0.48) | HSF1LTA4HKCNH2LOXL2HPGD | |
| SCHEMBL1334786 | 0.80 | HSF1 (0.50) | HSF1LTA4HKCNH2LOXL2HPGD | |
| SCHEMBL1334787 | 0.75 | LTA4H (0.50) | HSF1LTA4HKCNH2LOXL2HPGD | |
| SCHEMBL27943317 | 0.73 | HPGD (0.59) | LOXL2HPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL31010170 | 0.72 | LTA4H (0.58) | LTA4HKCNH2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29447341 | 0.70 | KCNH2 (0.59) | LTA4HKCNH2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6569005 | 0.69 | ATP4A (0.57) | LTA4HKCNH2ALDH1A1NPC1RAB9A | |
| SCHEMBL8413104 | 0.69 | HPGD (0.54) | LOXL2HPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7773349 | 0.69 | HTR1A (0.50) | LOXL2HPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL10351068 | 0.68 | HPGD (0.58) | LOXL2HPGDALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |