Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4806699 | 0.83 | ALDH1A1 (0.54) | L3MBTL1NPC1RAB9AALDH1A1RAD52 | |
| SCHEMBL7063741 | 0.80 | HTR1B (0.52) | GAANPSR1NPC1RAB9AALDH1A1 | |
| SCHEMBL7063234 | 0.80 | HTR1B (0.52) | GAANPSR1NPC1RAB9AALDH1A1 | |
| SCHEMBL7062951 | 0.80 | HTR1B (0.52) | GAANPSR1NPC1RAB9AALDH1A1 | |
| SCHEMBL6913785 | 0.79 | HTR1B (0.47) | GAANPSR1NPC1RAB9AALDH1A1 | |
| SCHEMBL14596904 | 0.75 | RAB9A (0.58) | L3MBTL1NPC1RAB9AALDH1A1RAD52 | |
| SCHEMBL14370170 | 0.72 | HTR1B (0.73) | GAAL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL5354642 | 0.72 | HTR1B (0.73) | GAAL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL14263999 | 0.72 | HTR1B (0.73) | GAAL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL7803574 | 0.71 | HTR1B (0.55) | GAANPSR1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025094-B1 | SUBSTITUTED INDAN DERIVATIVES | ASTRAZENECA AB (SE) | 2004-08-25 | — | — | EP | claimed |