Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570105 | 0.84 | SIGMAR1 (0.61) | CYP3A4CYP2C19SIGMAR1ALDH1A1TSHR | |
| SCHEMBL7979173 | 0.81 | L3MBTL1 (0.62) | L3MBTL1SIGMAR1HRH3 | |
| SCHEMBL19850993 | 0.81 | L3MBTL1 (0.62) | L3MBTL1SIGMAR1HRH3 | |
| SCHEMBL11205656 | 0.78 | ACHE (0.66) | HPGDSMN1; SMN2CYP3A4CYP2C19SIGMAR1 | |
| SCHEMBL12725 | 0.78 | ACHE (0.66) | HPGDSMN1; SMN2CYP3A4CYP2C19SIGMAR1 | |
| SCHEMBL12929 | 0.78 | ACHE (0.66) | HPGDSMN1; SMN2CYP3A4CYP2C19SIGMAR1 | |
| SCHEMBL491602 | 0.75 | HRH3 (0.68) | ALDH1A1HRH3 | |
| SCHEMBL12717 | 0.74 | CYP3A4 (0.66) | HPGDSMN1; SMN2CYP3A4CYP2C19SIGMAR1 | |
| SCHEMBL5304179 | 0.74 | CYP3A4 (0.66) | HPGDSMN1; SMN2CYP3A4CYP2C19SIGMAR1 | |
| SCHEMBL13083 | 0.74 | CYP3A4 (0.66) | HPGDSMN1; SMN2CYP3A4CYP2C19SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |