Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.61 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570161 | 0.86 | MAOB (0.48) | SIGMAR1ACHEMAOBHRH3NPC1 | |
| SCHEMBL6570124 | 0.84 | L3MBTL1 (0.52) | SIGMAR1ACHEALDH1A1HRH3CYP3A4 | |
| SCHEMBL13504052 | 0.79 | SIGMAR1 (0.88) | SIGMAR1ACHEALDH1A1USP2HRH3 | |
| SCHEMBL17285905 | 0.77 | SIGMAR1 (0.97) | SIGMAR1ACHEALDH1A1USP2CCR3 | |
| SCHEMBL152736 | 0.75 | ACHE (1.00) | SIGMAR1ACHEALDH1A1USP2HRH3 | |
| SCHEMBL491564 | 0.72 | SIGMAR1 (0.76) | SIGMAR1ACHEALDH1A1USP2HRH3 | |
| SCHEMBL24429026 | 0.71 | KDM4E (0.40) | ACHEALDH1A1HRH3KDM4EPOLB | |
| SCHEMBL156315 | 0.71 | ACHE (1.00) | SIGMAR1ACHEALDH1A1HRH3CCR3 | |
| SCHEMBL5966248 | 0.70 | GRM5 (0.50) | SIGMAR1MAOAMAOB | |
| Ammonia Solution, Strong SCHEMBL2945383 | 0.70 | ACHE (0.96) | SIGMAR1ACHEALDH1A1HRH3CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |