SCHEMBL6570225

SCHEMBL6570225

CCCCONCCc1c[c]ccc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
HPGD P15428 1/20 0.43
SIGMAR1 Q99720 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
TSHR P16473 1/20 0.35
CYP2D6 P10635 4/20 0.33
KCNH2 Q12809 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
STS P08842 2/20 0.32
MAPT P10636 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
AR P10275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6570269 0.81 SIGMAR1 (0.38) ALDH1A1HPGDSIGMAR1MEN1KMT2A
SCHEMBL2911080 0.81 SIGMAR1 (0.56) ALDH1A1HPGDSIGMAR1MEN1KMT2A
SCHEMBL8640855 0.78 ALDH1A1 (0.43) ALDH1A1HPGDMEN1KMT2ATSHR
SCHEMBL10713032 0.78 ALDH1A1 (0.43) ALDH1A1HPGDMEN1KMT2ATSHR
SCHEMBL57607 0.77 CA2 (0.40) ALDH1A1HPGDSIGMAR1NPC1RAB9A
SCHEMBL28475113 0.76 SIGMAR1 (0.59) ALDH1A1HPGDSIGMAR1MEN1KMT2A
SCHEMBL278144 0.76 TDP1 (0.47) ALDH1A1TSHRKCNH2LMNA
SCHEMBL533252 0.74 KCNH2 (0.46) ALDH1A1TSHRKCNH2LMNA
SCHEMBL20774553 0.74 KCNH2 (0.46) ALDH1A1TSHRKCNH2LMNA
SCHEMBL4865067 0.74 KCNH2 (0.46) ALDH1A1TSHRKCNH2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0463488-B2 O-Benzyl oxime ethers and fungicides containing them BASF AG (DE) 2004-04-21 EP claimed
EP-0463488-B2 O-Benzyl oxime ethers and fungicides containing them BASF AG (DE) 2004-04-21 EP disclosed
US-RE37839-E1 O-benzyloxime ethers and crop protection agents containing these compounds BASF AKTIENGESELLSCHAFT (DE) 2002-09-10 US disclosed
US-6326399-B1 CONTROLLING INSECTS, ARACHNIDS, NEMATODES BASF AKTIENGESELLSCHAFT (DE) 2001-12-04 US disclosed
US-6316459-B1 O-benzyloxime ethers and crop protection agents containing these compounds BASF AG (DE) 2001-11-13 US disclosed
US-6211190-B1 Pyrimidine derivatives, process and intermediate products for their preparation and pesticides or fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed