Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713032 | 0.93 | ALDH1A1 (0.43) | ALDH1A1HPGDTSHRHRH3CYP3A4 | |
| SCHEMBL18705909 | 0.84 | RAB9A (0.36) | MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL57607 | 0.82 | CA2 (0.40) | ALDH1A1HPGDKCNH2CYP3A4MAPK1 | |
| SCHEMBL10712656 | 0.81 | RAB9A (0.40) | HRH3KCNH2MAPK1MEN1KMT2A | |
| SCHEMBL27624397 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL278144 | 0.80 | TDP1 (0.47) | ALDH1A1TSHRKCNH2CYP3A4LMNA | |
| SCHEMBL33707 | 0.79 | MAPK1 (0.36) | ALDH1A1TSHRCYP3A4MAPK1MEN1 | |
| SCHEMBL263493 | 0.79 | KCNH2 (0.46) | ALDH1A1TSHRKCNH2CYP3A4LMNA | |
| SCHEMBL7296736 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGDTSHRHRH3KCNH2 | |
| SCHEMBL4865067 | 0.79 | KCNH2 (0.46) | ALDH1A1TSHRKCNH2CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510449-B1 | Acid-cleavable compounds, positive-working radiation-sensitive composition containing the same and radiation-sensitive recording material prepared therefrom | CLARIANT GMBH (DE) | 1998-08-05 | — | — | EP | disclosed |
| US-5286602-A | Acid-cleavable compounds, positive-working radiation-sensitive mixture containing these compounds, and radiation-sensitive recording material produced with this mixture | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-15 | — | — | US | disclosed |
| EP-0510449-A2 | Acid-cleavable compounds, positive-working radiation-sensitive composition containing the same and radiation-sensitive recording material prepared therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |