Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 6/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568765 | 0.89 | LMNA (0.48) | LMNARECQLCCR5F11POLB | |
| SCHEMBL6569865 | 0.81 | SMN1; SMN2 (0.46) | LMNAPIN1POLBSMN1; SMN2RIPK1 | |
| SCHEMBL1951857 | 0.81 | EEF2K (0.46) | LMNACCR5PIN1POLB | |
| SCHEMBL1951858 | 0.81 | EEF2K (0.46) | LMNACCR5PIN1POLB | |
| SCHEMBL1951861 | 0.81 | EEF2K (0.46) | LMNACCR5PIN1POLB | |
| SCHEMBL6568402 | 0.80 | PIN1 (0.62) | LMNAPIN1SMN1; SMN2 | |
| SCHEMBL6568413 | 0.80 | PIN1 (0.48) | LMNAPIN1TDP1SMN1; SMN2RIPK1 | |
| SCHEMBL6568573 | 0.80 | RIPK1 (0.55) | LMNAPIN1POLBRIPK1 | |
| SCHEMBL9829153 | 0.77 | ITGB3 (0.59) | LMNARECQLCCR5F11KCNQ3 | |
| SCHEMBL6568557 | 0.76 | PIN1 (0.44) | LMNAPIN1POLBSMN1; SMN2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156054-B1 | DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2004-04-14 | — | — | EP | claimed |
| US-6495533-B1 | TUMOR NECROSIS FACTOR INHIBITORS; RHEUMATOID ARTHRITIS, ULCERATIVE COLITIS, CROHN'S DISEASE, HEPATITIS, SEPSIS, HEMORRHAGIC SHOCK, MULTIPLE SCLEROSIS, CEREBRAL INFARCTION, DIABETES, INTERSTITIAL PNEUMONIA, PAIN, HIV | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-12-17 | — | — | US | claimed |
| EP-1156054-A1 | DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | claimed |