Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | PON1 | P27169 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569246 | 0.94 | ALDH1A1 (0.37) | ALDH1A1POLBLMNAHTTMAPK1 | |
| SCHEMBL28609664 | 0.81 | KDM4E (0.40) | ALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL6570547 | 0.81 | KDM4E (0.40) | ALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL6568369 | 0.77 | MEN1 (0.38) | ALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL6569099 | 0.77 | TAAR1 (0.36) | LMNAHPGD | |
| SCHEMBL6570579 | 0.75 | CALM1 (0.38) | HTTMAPK1TRPV1NPSR1HPGD | |
| SCHEMBL6569068 | 0.75 | ALOX15 (0.39) | LMNAHTTSMN1; SMN2MAPTALOX15 | |
| SCHEMBL6567367 | 0.75 | KDM4E (0.40) | ALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL28614086 | 0.75 | KDM4E (0.40) | ALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL6569150 | 0.74 | USP2 (0.36) | ALDH1A1SMN1; SMN2NPSR1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405851-A1 | Method for producing seven-membered diether compounds and intermediates thereof | Takasago International Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |