Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 17/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.36 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049183 | 0.95 | RIPK1 (0.44) | RIPK1FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7429151 | 0.79 | FKBP1A (0.47) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7771830 | 0.77 | FKBP1A (0.49) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL6570600 | 0.75 | FKBP1A (0.47) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL5275386 | 0.71 | FKBP1A (0.41) | RIPK1FKBP1AFKBP4FKBP5 | |
| SCHEMBL4677127 | 0.71 | FKBP1A (0.66) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL17881960 | 0.69 | RIPK1 (0.71) | RIPK1 | |
| SCHEMBL7433188 | 0.69 | FKBP1A (0.59) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7422008 | 0.68 | FKBP1A (0.61) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL15185124 | 0.67 | RIPK1 (0.49) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404325-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002096420-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| EP-1233945-A1 | HETEROCYCLIC KETONE AND THIOESTER COMPOUNDS AND USES | GPI NIL Holdings, Inc. (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001038304-A1 | HETEROCYCLIC KETONE AND THIOESTER COMPOUNDS AND USES | GPI NIL HOLDINGS, INC. (US) | 2001-05-31 | — | — | WO | disclosed |