Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 20/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.42 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433188 | 0.79 | FKBP1A (0.59) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7424334 | 0.76 | FKBP1A (0.64) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7912814 | 0.75 | FKBP1A (1.00) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL6049183 | 0.74 | RIPK1 (0.44) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL5966178 | 0.73 | FKBP1A (0.95) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL12311524 | 0.71 | FKBP1A (0.67) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL28331561 | 0.71 | FKBP1A (0.74) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7938022 | 0.70 | FKBP1A (0.65) | FKBP1A | |
| SCHEMBL5966165 | 0.70 | FKBP1A (0.49) | FKBP1A | |
| SCHEMBL5966048 | 0.69 | FKBP1A (0.63) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127049-A1 | BRIDGED HETEROCYCLIC DERIVATIVES | GPI NIL Holdings, Inc. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000016603-A2 | BRIDGED HETEROCYCLIC DERIVATIVES | GPI NIL HOLDINGS, INC. (US) | 2000-03-30 | — | — | WO | disclosed |