Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 16/20 | 0.39 |
| ▸ | HRH1 | P35367 | 15/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568905 | 0.80 | HRH1 (0.46) | CCR3HRH1KCNH2UTS2RP2RX7 | |
| SCHEMBL6569252 | 0.78 | HRH1 (0.54) | CCR3HRH1KCNH2 | |
| SCHEMBL6570664 | 0.72 | SLC6A2 (0.48) | CCR3HRH1KCNH2UTS2RP2RX7 | |
| SCHEMBL6568478 | 0.69 | HRH1 (0.48) | CCR3HRH1KCNH2UTS2R | |
| SCHEMBL6569446 | 0.68 | CCR3 (0.56) | CCR3HRH1KCNH2UTS2R | |
| SCHEMBL6647507 | 0.68 | CCR3 (0.47) | CCR3HRH1KCNH2 | |
| SCHEMBL6567411 | 0.67 | HRH1 (0.46) | CCR3HRH1KCNH2P2RX7 | |
| SCHEMBL6569229 | 0.67 | HRH1 (0.47) | CCR3HRH1KCNH2UTS2RP2RX7 | |
| SCHEMBL7016612 | 0.65 | HRH1 (0.41) | CCR3HRH1KCNH2UTS2RP2RX7 | |
| SCHEMBL6568359 | 0.65 | CCR8 (0.41) | CCR3HRH1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404667-A1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003004487-A1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2003-01-16 | — | — | WO | disclosed |