SCHEMBL6570705

SCHEMBL6570705

Cc1ccccc1-n1c2ccccc2c2cc3c(cc21)c1ccccc1n3-c1ccccc1C

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
ALKBH5 Q6P6C2 1/20 0.43
FTO Q9C0B1 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
LMNA P02545 1/20 0.42
RAB9A P51151 1/20 0.42
KDM4E B2RXH2 3/20 0.42
ATM Q13315 1/20 0.42
NOTUM Q6P988 1/20 0.40
GPR3 P46089 1/20 0.40
KLK7 P49862 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
POLB P06746 1/20 0.38
NQO2 P16083 1/20 0.38
KMT2A Q03164 1/20 0.37
MGLL Q99685 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6552455 0.92 TSHR (0.53) TSHRALDH1A1SMN1; SMN2ALKBH5FTO
SCHEMBL21037885 0.90 TSHR (0.46) TSHRALDH1A1SMN1; SMN2ALKBH5FTO
SCHEMBL17166722 0.87 TSHR (0.44) TSHRALDH1A1SMN1; SMN2ALKBH5FTO
SCHEMBL27120040 0.84 TSHR (0.41) TSHRALDH1A1SMN1; SMN2ALKBH5FTO
SCHEMBL18676971 0.84 TSHR (0.41) TSHRALDH1A1SMN1; SMN2ALKBH5FTO
SCHEMBL18540682 0.84 TSPO (0.44) TSHRALDH1A1SMN1; SMN2ALKBH5FTO
SCHEMBL21037653 0.83 TSPO (0.45) TSHRALDH1A1SMN1; SMN2ALKBH5FTO
SCHEMBL25809743 0.83 RXRA (0.42) TSHRALDH1A1SMN1; SMN2L3MBTL1LMNA
SCHEMBL25640750 0.83 ALKBH5 (0.55) TSHRALDH1A1SMN1; SMN2ALKBH5FTO
SCHEMBL15435756 0.82 L3MBTL1 (0.46) TSHRALDH1A1SMN1; SMN2ALKBH5FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0908787-B1 Indolocarbazole Photoconductors XEROX CORP (US) 2004-04-14 EP claimed