Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570768 | 0.94 | KDM4E (0.44) | KDM4ELMNAALDH1A1CA12CA1 | |
| SCHEMBL3855292 | 0.81 | LMNA (0.37) | KDM4ELMNAALDH1A1CA12CA1 | |
| SCHEMBL5156805 | 0.81 | L3MBTL1 (0.35) | KDM4EALDH1A1POLBL3MBTL1TSHR | |
| SCHEMBL5952565 | 0.78 | NPC1 (0.50) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL3208573 | 0.78 | ATM (0.50) | KDM4ELMNAALDH1A1L3MBTL1NPC1 | |
| SCHEMBL7234945 | 0.77 | CA12 (0.60) | KDM4ELMNAALDH1A1CA12CA1 | |
| SCHEMBL9121827 | 0.77 | CA12 (0.60) | KDM4ELMNAALDH1A1CA12CA1 | |
| SCHEMBL2772131 | 0.76 | PLA2G2A (0.67) | PLA2G2ARAB9AMAPTTSHR | |
| Methyl Alcohol SCHEMBL28269742 | 0.75 | CA12 (0.58) | KDM4ELMNAALDH1A1CA12CA1 | |
| SCHEMBL2720868 | 0.74 | PTPN11 (0.46) | KDM4EALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140072-B1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-04-14 | — | — | EP | disclosed |