Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7133804 | 0.88 | EPHX2 (0.36) | EPHX2F10C3AR1TPSAB1NPC1 | |
| SCHEMBL7133816 | 0.88 | EPHX2 (0.36) | EPHX2F10C3AR1TPSAB1NPC1 | |
| SCHEMBL27576022 | 0.84 | CTSK (0.39) | EPHX2F10TPSAB1FOLH1F2 | |
| SCHEMBL757757 | 0.80 | C3AR1 (0.39) | EPHX2F10C3AR1TPSAB1NPC1 | |
| SCHEMBL757758 | 0.80 | C3AR1 (0.39) | EPHX2F10C3AR1TPSAB1NPC1 | |
| Hydrochloric Acid SCHEMBL27905179 | 0.79 | FOLH1 (0.36) | F10C3AR1TPSAB1NPC1FOLH1 | |
| SCHEMBL16318658 | 0.79 | MTNR1A (0.37) | EPHX2F10C3AR1FOLH1F2 | |
| SCHEMBL11218452 | 0.78 | CES2 (0.41) | F2PRSS1NAAAHDAC1HDAC6 | |
| SCHEMBL28986669 | 0.77 | ALOX15 (0.37) | ITGB3ITGA2B | |
| SCHEMBL9802532 | 0.77 | CNR1 (0.36) | C3AR1FOLH1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1407273-A2 | METHODS OF ASSESSING WOLFRAMIN PROTEIN ACTIVITY | PHARMACIA & UPJOHN COMPANY (US) | 2004-04-14 | — | — | EP | disclosed |
| WO-2002063307-A2 | METHODS OF ASSESSING WOLFRAMIN PROTEIN ACTIVITY | PHARMACIA & UPJOHN COMPANY (US) | 2002-08-15 | — | — | WO | disclosed |