Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27569671 | 0.82 | LTA4H (0.56) | LTA4HTSHRLMNAHTT | |
| SCHEMBL9493994 | 0.82 | LTA4H (0.57) | LTA4HTSHRSRD5A2NR1H2BAX | |
| SCHEMBL212179 | 0.81 | LMNA (0.52) | TSHRLMNA | |
| SCHEMBL13594208 | 0.81 | LMNA (0.52) | TSHRLMNA | |
| Ammonia Solution, Strong SCHEMBL27973477 | 0.80 | LTA4H (0.55) | LTA4HTSHRSRD5A2NR1H2BAX | |
| SCHEMBL18585352 | 0.79 | LMNA (0.50) | TSHRLMNA | |
| SCHEMBL10162228 | 0.78 | ALDH1A1 (0.54) | LTA4HTSHRNR1H2BAXNPY5R | |
| SCHEMBL5607146 | 0.78 | TDP1 (0.42) | TSHRLMNA | |
| SCHEMBL7109235 | 0.78 | ALDH1A1 (0.50) | TSHR | |
| SCHEMBL2997242 | 0.78 | CHRNB2 (0.47) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |