Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | NOS2 | P35228 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | CFD | P00746 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6571970 | 0.98 | NOS3 (0.42) | LOXL2HTR7PNMTENPP2NOS3 | |
| SCHEMBL27747310 | 0.86 | LOXL2 (0.43) | LOXL2HTR7PNMTENPP2NOS3 | |
| SCHEMBL3790111 | 0.86 | MAP4K4 (0.46) | LOXL2PNMTENPP2CYP3A4TAAR1 | |
| SCHEMBL7691367 | 0.84 | HTR7 (0.38) | HTR7ALDH1A1SMN1; SMN2CYP3A4TAAR1 | |
| SCHEMBL27506720 | 0.84 | BCL2 (0.41) | HTR7ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL27503727 | 0.83 | LOXL2 (0.54) | LOXL2TAAR1CYP19A1CSNK2A1 | |
| SCHEMBL27447980 | 0.83 | LOXL2 (0.45) | LOXL2HTR7PNMTENPP2NOS3 | |
| SCHEMBL6572315 | 0.83 | BACE1 (0.49) | LOXL2HTR7PNMTENPP2NOS3 | |
| SCHEMBL22345011 | 0.82 | MAOA (0.44) | ALDH1A1SMN1; SMN2CYP3A4TAAR1 | |
| SCHEMBL3790240 | 0.81 | ALDH1A1 (0.54) | LOXL2HTR7PNMTENPP2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| CN-101208406-A | Synthesis of phenyl-substituted polyfluoroanthenes and the use thereof | BASF AG (DE) | 2008-06-25 | — | — | CN | disclosed |
| CN-100383150-C | Method for producing tris-ortho-metallated organometallic complexes and use of said complexes in OLEDs | BASF AG (DE) | 2008-04-23 | — | — | CN | disclosed |
| CN-1816556-A | Method for producing tris-ortho-metallated complexes and use of such complexes in oleds | BASF AG (DE) | 2006-08-09 | — | — | CN | disclosed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |