SCHEMBL6572247

SCHEMBL6572247

COCCN(CCOC)c1ccc(N)cc1-c1ccc(C=O)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH3A1 P30838 5/20 0.38
ALDH1A1 P00352 5/20 0.38
ALDH1A3 P47895 4/20 0.38
RET P07949 2/20 0.33
DRD2 P14416 1/20 0.33
DRD1 P21728 1/20 0.33
DRD4 P21917 1/20 0.33
DRD5 P21918 1/20 0.33
DRD3 P35462 1/20 0.33
FDPS P14324 1/20 0.32
CYP2A6 P11509 1/20 0.32
PTGER4 P35408 1/20 0.32
CCNB2 O95067 1/20 0.31
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
CDK5 Q00535 1/20 0.31
CDK5R1 Q15078 1/20 0.31
CCNB3 Q8WWL7 1/20 0.31
GAA P10253 1/20 0.31
CRHR1 P34998 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6572090 0.88 CRHR1 (0.34) ALDH1A1GAACRHR1TDP1
SCHEMBL6570897 0.87 CRHR1 (0.31) CRHR1CYP19A1NQO2
SCHEMBL6571906 0.86 ALDH3A1 (0.36) ALDH3A1ALDH1A1ALDH1A3PTGER4CRHR1
SCHEMBL6572307 0.84 ALDH3A1 (0.38) ALDH3A1ALDH1A1ALDH1A3RETDRD2
SCHEMBL6571013 0.84 CRHR1 (0.38) ALDH1A1CRHR1HPGDTDP1
SCHEMBL6574535 0.83 FDPS (0.43) ALDH3A1ALDH1A1ALDH1A3FDPSCYP19A1
SCHEMBL6572104 0.83 CRHR1 (0.32) CRHR1
SCHEMBL6572455 0.83 USP7 (0.35) ALDH1A1GAACRHR1HPGD
SCHEMBL6571986 0.83 MEN1 (0.41) CRHR1
SCHEMBL6571975 0.83 GRM2 (0.38) ALDH1A1CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP claimed
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP disclosed
US-6500213-B1 Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives WELLA AKTIENGESELLSCHAFT (DE) 2002-12-31 US disclosed
EP-1051143-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES Wella Aktiengesellschaft (DE) 2000-11-15 EP disclosed
WO-1999059527-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO disclosed