SCHEMBL6571906

SCHEMBL6571906

COCCN(CCOC)c1ccc(N)cc1-c1cccc(C=O)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH3A1 P30838 3/20 0.36
ALDH1A3 P47895 3/20 0.36
ALDH1A1 P00352 1/20 0.36
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CRHR1 P34998 2/20 0.33
EGFR P00533 1/20 0.33
SRC P12931 1/20 0.33
PTGER4 P35408 1/20 0.32
MAOA P21397 3/20 0.32
MAOB P27338 3/20 0.32
BRD4 O60885 1/20 0.32
TRIM24 O15164 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6572247 0.86 ALDH3A1 (0.38) ALDH3A1ALDH1A3ALDH1A1TDP1CRHR1
SCHEMBL6572255 0.86 CRHR1 (0.38) ALDH1A1CRHR1MAOABRD4MAP4K4
SCHEMBL6570947 0.84 TRIM24 (0.37) ALDH3A1ALDH1A3ALDH1A1CA12CA1
SCHEMBL6573087 0.83 CRHR1 (0.40) ALDH1A1NPC1RAB9ACRHR1MAP4K4
SCHEMBL6572624 0.81 MAP4K4 (0.44) CRHR1MAOBMAP4K4KMT2A
SCHEMBL6571546 0.81 CRHR1 (0.42) ALDH1A1CRHR1MAOBMEN1KMT2A
SCHEMBL6571031 0.81 PIK3CG (0.38) ALDH1A1CA12CA1CA2CA9
SCHEMBL6571312 0.81 ALDH1A1 (0.44) ALDH1A1EGFRSRCMAOBCYP19A1
SCHEMBL6572721 0.81 KDM4E (0.35) ALDH1A1NPC1RAB9ACRHR1MEN1
SCHEMBL6574535 0.80 FDPS (0.43) ALDH3A1ALDH1A3ALDH1A1TDP1TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP claimed
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP disclosed
US-6500213-B1 Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives WELLA AKTIENGESELLSCHAFT (DE) 2002-12-31 US disclosed
EP-1051143-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES Wella Aktiengesellschaft (DE) 2000-11-15 EP disclosed
WO-1999059527-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO disclosed