SCHEMBL6572306

SCHEMBL6572306

C[C]Cc1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.52
ESR2 Q92731 7/20 0.50
TAAR1 Q96RJ0 4/20 0.48
SLC6A2 P23975 2/20 0.48
ABAT P80404 1/20 0.46
CA2 P00918 2/20 0.44
TMEM97 Q5BJF2 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
CYP2C19 P33261 1/20 0.42
HTR3A P46098 1/20 0.42
BACE1 P56817 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
IDO1 P14902 1/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
CA12 O43570 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1548710 0.86 ALDH1A1 (0.35) ESR1ESR2ALDH1A1IDO1CYP3A4
SCHEMBL28690106 0.80 ESR1 (0.48) ESR1ESR2TAAR1SLC6A2ABAT
SCHEMBL16904622 0.78 ESR1 (0.55) ESR1ESR2TAAR1SLC6A2ABAT
SCHEMBL4222886 0.76 IDO1 (0.48) TAAR1ALDH1A1IDO1MAPT
SCHEMBL910567 0.74 ESR1 (0.57) ESR1ESR2TAAR1SLC6A2ABAT
SCHEMBL4222881 0.74 SLC6A2 (0.48) TAAR1SLC6A2KDM4EALDH1A1IDO1
SCHEMBL4219890 0.74 PYCR1 (0.44) TAAR1ALDH1A1IDO1ALOX15
SCHEMBL9331371 0.74 TRPA1 (0.52) ESR1ESR2TAAR1SLC6A2ABAT
SCHEMBL448467 0.74 MMP3 (0.57) ESR1ESR2TAAR1SLC6A2ABAT
SCHEMBL357871 0.74 ESR1 (0.50) ESR1ESR2TAAR1SLC6A2ABAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1290058-A2 PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2003-03-12 EP claimed
WO-2001088013-A2 PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC (US) 2001-11-22 WO claimed
EP-1406885-A1 PROCESS FOR MANUFACTURING AN A-DIHYDROXY DERIVATIVE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2004-04-14 EP disclosed
EP-1290058-A2 PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2003-03-12 EP disclosed
WO-2003004481-A1 PROCESS FOR MANUFACTURING AN A-DIHYDROXY DERIVATIVE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2003-01-16 WO disclosed
WO-2001088013-A2 PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC (US) 2001-11-22 WO disclosed
EP-0295126-B1 ARYLAMINE-CONTAINING POLYHYDROXY ETHER RESINS XEROX CORPORATION (US) 1993-08-04 EP disclosed
US-4818650-A Arylamine containing polyhydroxy ether resins and system utilizing arylamine containing polyhydroxyl ether resins XEROX CORPORATION (US) 1989-04-04 US disclosed
EP-0295126-A2 Arylamine-containing polyhydroxy ether resins XEROX CORPORATION (US) 1988-12-14 EP disclosed