SCHEMBL6573943

SCHEMBL6573943

CC(O)(O)Nc1ccc(N)c(/C=N/NC(=N)N)c1

nearest known ligand 0.31

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.31
MAPT P10636 2/20 0.31
MEN1 O00255 2/20 0.31
USP2 O75604 2/20 0.31
KMT2A Q03164 2/20 0.31
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
LMNA P02545 2/20 0.31
ALOX12 P18054 1/20 0.31
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
GCGR P47871 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6576386 0.87 KMT2A (0.43) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL6574010 0.77 GAA (0.35) ALDH1A1MAPTMEN1USP2KMT2A
SCHEMBL6573944 0.76 LMNA (0.32) ALDH1A1MAPTMEN1USP2KMT2A
SCHEMBL6573496 0.76 KMT2A (0.44) ALDH1A1MAPTMEN1USP2KMT2A
Hydrochloric Acid SCHEMBL7266202 0.75 KMT2A (0.43) ALDH1A1MAPTMEN1USP2KMT2A
SCHEMBL6576274 0.74 MAOA (0.44) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL6572554 0.74 L3MBTL1 (0.38) ALDH1A1MAPTMEN1USP2KMT2A
SCHEMBL21519509 0.70 GAA (0.47) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL16993761 0.67 MAPT (0.53) ALDH1A1MAPTMEN1USP2KMT2A
SCHEMBL22017069 0.67 LMNA (0.61) ALDH1A1MAPTMEN1USP2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1120405-B1 Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes OREAL (FR) 2004-10-27 EP claimed
US-20010034913-A1 Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes L'OREAL S.A. (FR) 2001-11-01 US claimed
EP-1120405-A2 Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes L'OREAL (FR) 2001-08-01 EP claimed
EP-1120405-B1 Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes OREAL (FR) 2004-10-27 EP disclosed
US-6652600-B2 Oxidation color dye L'OREAL S.A. (FR) 2003-11-25 US disclosed
US-20010034913-A1 Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes L'OREAL S.A. (FR) 2001-11-01 US disclosed
EP-1120405-A2 Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes L'OREAL (FR) 2001-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010034913-A1 Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes KRT18, OGG1, UNG ALDH1A1 785/4885MAPT 1802/4885MEN1 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.