SCHEMBL657538

SCHEMBL657538

Cc1ccc(CC(=O)Cl)cc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.55
NPC1 O15118 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
CTBP2 P56545 1/20 0.52
KMT2A Q03164 5/20 0.50
MEN1 O00255 4/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 3/20 0.48
TDP1 Q9NUW8 1/20 0.48
CNR2 P34972 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
LMNA P02545 2/20 0.46
GAA P10253 1/20 0.46
EGFR P00533 1/20 0.45
ERBB2 P04626 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11843342 0.92 CA2 (0.52) RAB9ANPC1L3MBTL1CTBP2KMT2A
SCHEMBL11338131 0.92 L3MBTL1 (0.61) RAB9ANPC1L3MBTL1CTBP2KMT2A
SCHEMBL4194796 0.87 CA2 (0.46) RAB9ANPC1L3MBTL1CTBP2ALDH1A1
Toluene SCHEMBL4236990 0.81 SMN1; SMN2 (0.51) RAB9AL3MBTL1CTBP2KMT2AALDH1A1
SCHEMBL25046253 0.81 CTBP2 (0.52) RAB9ANPC1L3MBTL1CTBP2KMT2A
SCHEMBL9449852 0.81 CA2 (0.64) ALDH1A1TDP1LMNA
SCHEMBL155192 0.81 ALDH1A1 (0.52) RAB9AL3MBTL1KMT2AMEN1ALDH1A1
SCHEMBL28455325 0.80 LMNA (0.54) KMT2AMEN1ALDH1A1HPGDLMNA
SCHEMBL4940818 0.80 L3MBTL1 (0.62) RAB9ANPC1L3MBTL1CTBP2KMT2A
SCHEMBL2525145 0.78 CA2 (0.62) RAB9ANPC1L3MBTL1CTBP2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1931693-A2 PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES CHEMAGIS LTD. (IL) 2008-06-18 EP claimed
WO-2007027564-A2 PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES CHEMAGIS LTD. (IL) 2007-03-08 WO claimed
US-4481369-A VIA TRICARBONYL(TRIPHENYLPOSPHINE) COBALTATE ETHYL CORPORATION (US) 1984-11-06 US claimed
US-4481368-A Process for preparing α-keto-carboxylic acids from acyl halides ETHYL CORPORATION (US) 1984-11-06 US claimed
US-4272502-A Process for preparing gaseous hydrogen chloride from dilute aqueous hydrochloric acid CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DE) 1981-06-09 US claimed
EP-4709710-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY Arcturus Therapeutics, Inc. (US) 2026-03-18 EP disclosed
CN-120058572-A Preparation method of eremophilone intermediate 江苏百奥信康医药科技有限公司 2025-05-30 CN disclosed
WO-2025093639-A1 RESIN COMPOSITION FOR THREE-DIMENSIONAL PRINTING CUBICURE GMBH (AT) 2025-05-08 WO disclosed
EP-4549150-A1 RESIN COMPOSITION FOR THREE-DIMENSIONAL PRINTING Cubicure GmbH (AT) 2025-05-07 EP disclosed
CN-119874597-A Preparation method of medical intermediate 百泰生物药业有限公司 2025-04-25 CN disclosed
US-20250067749-A1 A Diazo Compound And A Preparation Method And A Use Thereof PEKING UNIVERSITY (CN) 2025-02-27 US disclosed
US-20250066378-A1 SPIRO-OXAZOLONES HOFFMANN-LA ROCHE INC. (US) 2025-02-27 US disclosed
US-4138485-A ANTILIPEMIC AGENTS KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1979-02-06 US disclosed
US-4138581-A BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS STERLING DRUGS INC. (US) 1979-02-06 US disclosed
US-4096267-A (1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio) alkanoic acids, and derivatives thereof MERCK & CO., INC. (US) 1978-06-20 US disclosed
US-4079141-A ANALGESICS AMERICAN HOECHST CORPORATION (US) 1978-03-14 US disclosed
US-4067726-A 3-Ureido phenylacetamide herbicides BAYER AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed
US-4039413-A OXYGEN-FREE, UV OR VISIBLE LIGHT, ORGANIC PEROXIDE, ACRYLIC POLYMERSON ROHM GMBH (DT) 1977-08-02 US disclosed
US-4000154-A 3-Substituted-6β-(amino- and acylamino)-7-oxo-1,3-diazabicyclo[3.2.0]-h SMITHKLINE CORPORATION (US) 1976-12-28 US disclosed
US-3984552-A 6-Oxo-7-substituted and 7,7-disubstituted-6H-indeno-[5,4-b]furan (and thiophene) carboxylic acids MERCK & CO., INC. (US) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066378-A1 SPIRO-OXAZOLONES AVPR1A, AVPR1B, AVPR2 RAB9A 1528/4885NPC1 3185/4885L3MBTL1 3163/4885
US-20250067749-A1 A Diazo Compound And A Preparation Method And A Use Thereof DAO, DDC, DDO RAB9A 1335/4885NPC1 3114/4885L3MBTL1 4160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.