Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1A1 | P14550 | 13/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 13/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575507 | 0.87 | AKR1A1 (0.55) | AKR1A1AKR1B1GPR84 | |
| SCHEMBL6576328 | 0.87 | GPR84 (0.55) | AKR1A1AKR1B1GPR84KMT2A | |
| SCHEMBL6576292 | 0.85 | AKR1A1 (0.56) | AKR1A1AKR1B1GPR84 | |
| SCHEMBL6576362 | 0.85 | AKR1A1 (0.56) | AKR1A1AKR1B1 | |
| SCHEMBL6576372 | 0.85 | AKR1A1 (0.56) | AKR1A1AKR1B1GPR84 | |
| SCHEMBL6577907 | 0.85 | AKR1A1 (0.56) | AKR1A1AKR1B1 | |
| SCHEMBL6578380 | 0.77 | AKR1A1 (0.55) | AKR1A1AKR1B1 | |
| SCHEMBL6578352 | 0.75 | AKR1A1 (0.54) | AKR1A1AKR1B1 | |
| SCHEMBL8660288 | 0.72 | AKR1A1 (0.62) | AKR1A1AKR1B1 | |
| SCHEMBL6575586 | 0.72 | GPR84 (0.58) | AKR1A1AKR1B1MAPTGPR84MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135124-B1 | ANTIHYPERTRIGLYCERIDEMIC, ANTIHYPERGLYCEMIC, ANTI-ANGIOGENIC AND WOUND HEALING SUBSTITUDED INDOLEALKANOIC ACIDS | INST FOR PHARM DISCOVERY INC (US) | 2004-04-28 | — | — | EP | disclosed |