Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | OGG1 | O15527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494805 | 0.76 | TSHR (0.59) | MEN1KMT2ACYP3A4TSHRMAPK1 | |
| SCHEMBL5865631 | 0.74 | NOTUM (0.53) | MEN1KMT2ACYP3A4TSHRMAPK1 | |
| SCHEMBL21836896 | 0.74 | TTR (0.45) | MEN1KMT2ATSHRMAPK1L3MBTL1 | |
| SCHEMBL29624982 | 0.74 | TTR (0.45) | MEN1KMT2ATSHRMAPK1L3MBTL1 | |
| SCHEMBL5865578 | 0.72 | MAPT (0.46) | MEN1KMT2ACYP3A4TSHRMAPK1 | |
| SCHEMBL9494935 | 0.71 | MEN1 (0.48) | MEN1KMT2ACYP3A4TSHRMAPK1 | |
| SCHEMBL9494493 | 0.69 | TSHR (0.77) | MEN1KMT2ACYP3A4TSHRMAPK1 | |
| SCHEMBL25949222 | 0.69 | NOTUM (0.58) | MEN1KMT2ATSHRMAPK1ATM | |
| SCHEMBL5865698 | 0.69 | CCR2 (0.39) | MEN1KMT2ACYP3A4TSHRMAPK1 | |
| SCHEMBL5865690 | 0.69 | GPR35 (0.49) | MEN1KMT2ATSHRMAPK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412311-A1 | NOVEL TREATMENT OF ADRENOCORTICAL HYPERSECRETION AND TUMOUR GROWTH | Brandt, Ingvar (SE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003002495-A1 | NOVEL TREATMENT OF ADRENOCORTICAL HYPERSECRETION AND TUMOUR GROWTH | BRANDT INGVAR (SE) | 2003-01-09 | — | — | WO | disclosed |