Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1A1 | P14550 | 13/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 13/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577907 | 0.91 | AKR1A1 (0.56) | AKR1A1AKR1B1HTR2APCSK9 | |
| SCHEMBL6576328 | 0.89 | GPR84 (0.55) | AKR1A1AKR1B1HTR2A | |
| SCHEMBL6576335 | 0.85 | AKR1A1 (0.53) | AKR1A1AKR1B1 | |
| SCHEMBL6575507 | 0.82 | AKR1A1 (0.55) | AKR1A1AKR1B1HTR2A | |
| SCHEMBL6576372 | 0.80 | AKR1A1 (0.56) | AKR1A1AKR1B1 | |
| SCHEMBL6577852 | 0.79 | AKR1A1 (0.62) | AKR1A1AKR1B1HTR1D | |
| SCHEMBL420815 | 0.72 | AKR1A1 (1.00) | AKR1A1AKR1B1 | |
| SCHEMBL18383116 | 0.72 | HTR1D (0.69) | HTR1DHTR2APCSK9 | |
| SCHEMBL6578380 | 0.70 | AKR1A1 (0.55) | AKR1A1AKR1B1 | |
| SCHEMBL443358 | 0.70 | AKR1A1 (1.00) | AKR1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135124-B1 | ANTIHYPERTRIGLYCERIDEMIC, ANTIHYPERGLYCEMIC, ANTI-ANGIOGENIC AND WOUND HEALING SUBSTITUDED INDOLEALKANOIC ACIDS | INST FOR PHARM DISCOVERY INC (US) | 2004-04-28 | — | — | EP | disclosed |