Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.55 |
| ▸ | AKR1A1 | P14550 | 5/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.54 |
| ▸ | MPO | P05164 | 6/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575507 | 0.91 | AKR1A1 (0.55) | GPR84AKR1A1AKR1B1HTR2A | |
| SCHEMBL6576292 | 0.89 | AKR1A1 (0.56) | GPR84AKR1A1AKR1B1HTR2ATRPM8 | |
| SCHEMBL6576362 | 0.89 | AKR1A1 (0.56) | AKR1A1AKR1B1HTR2A | |
| SCHEMBL6576335 | 0.87 | AKR1A1 (0.53) | GPR84AKR1A1AKR1B1KMT2A | |
| SCHEMBL6577907 | 0.82 | AKR1A1 (0.56) | AKR1A1AKR1B1HTR2A | |
| SCHEMBL6576372 | 0.82 | AKR1A1 (0.56) | GPR84AKR1A1AKR1B1 | |
| SCHEMBL6577852 | 0.81 | AKR1A1 (0.62) | AKR1A1AKR1B1TRPM8HTR1AKMT2A | |
| SCHEMBL18383118 | 0.73 | GPR84 (1.00) | GPR84MPOHTR2ATRPM8HTR1A | |
| SCHEMBL30482437 | 0.73 | GPR84 (1.00) | GPR84MPOHTR2ATRPM8HTR1A | |
| SCHEMBL30913603 | 0.73 | GPR84 (1.00) | GPR84MPOHTR2ATRPM8HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135124-B1 | ANTIHYPERTRIGLYCERIDEMIC, ANTIHYPERGLYCEMIC, ANTI-ANGIOGENIC AND WOUND HEALING SUBSTITUDED INDOLEALKANOIC ACIDS | INST FOR PHARM DISCOVERY INC (US) | 2004-04-28 | — | — | EP | disclosed |