Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.43 |
| ▸ | SHBG | P04278 | 3/20 | 0.43 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497888 | 1.00 | GPBAR1 (0.43) | GPBAR1SHBGSERPINA6CYP3A4HSD17B10 | |
| SCHEMBL6446959 | 1.00 | GPBAR1 (0.43) | GPBAR1SHBGSERPINA6CYP3A4HSD17B10 | |
| SCHEMBL3842363 | 0.85 | GPBAR1 (0.59) | GPBAR1SHBGSERPINA6CYP3A4HSD17B10 | |
| SCHEMBL11516238 | 0.85 | GPBAR1 (0.59) | GPBAR1SHBGSERPINA6CYP3A4HSD17B10 | |
| SCHEMBL6577636 | 0.85 | GPBAR1 (0.59) | GPBAR1SHBGSERPINA6CYP3A4HSD17B10 | |
| SCHEMBL6804965 | 0.82 | SHBG (0.35) | GPBAR1SHBGNR3C1ARCYP19A1 | |
| SCHEMBL4438158 | 0.82 | SHBG (0.35) | GPBAR1SHBGNR3C1ARCYP19A1 | |
| SCHEMBL497582 | 0.82 | SHBG (0.35) | GPBAR1SHBGNR3C1ARCYP19A1 | |
| SCHEMBL497634 | 0.79 | G6PD (0.61) | GPBAR1SHBGSERPINA6CYP3A4HSD17B10 | |
| SCHEMBL5530806 | 0.77 | GPBAR1 (0.69) | GPBAR1SHBGSERPINA6CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050159366-A1 | Pharmaceutical compositions and treatment methods - 8 | BIOVIE INC. | 2005-07-21 | — | — | US | disclosed |
| US-20050075321-A1 | Neurological disorder treatment methods | BIOVIE INC. | 2005-04-07 | — | — | US | disclosed |
| EP-1422234-A2 | Immunomodulatory steroids, in particular the hemihydrate of 16.alpha.-bromoepiandrosterone | Hollis-Eden Pharmaceuticals Inc. (US) | 2004-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075321-A1 | Neurological disorder treatment methods | HSD17B1, HSD17B3, HSD3B1 | GPBAR1 649/4885SHBG 157/4885SERPINA6 78/4885 |
| US-20050159366-A1 | Pharmaceutical compositions and treatment methods - 8 | HSD17B7, NR5A1, HSD3B1 | GPBAR1 174/4885SHBG 37/4885SERPINA6 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.