Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.68 |
| ▸ | CTSB | P07858 | 1/20 | 0.68 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 9/20 | 0.50 |
| ▸ | CTSS | P25774 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577984 | 0.89 | CTSK (0.64) | CTSKCTSBCCR1CTSLCTSS | |
| SCHEMBL6578517 | 0.87 | CTSK (0.90) | CTSKCTSBTAS1R3TAS1R1CTSL | |
| SCHEMBL6580544 | 0.85 | CTSK (0.59) | CTSKCTSBCTSLCTSS | |
| SCHEMBL6580537 | 0.85 | TAS1R3 (0.55) | CTSKCTSBTAS1R3TAS1R1CCR1 | |
| SCHEMBL6578370 | 0.84 | CTSK (0.55) | CTSKCTSBCTSLCTSS | |
| SCHEMBL6580957 | 0.84 | CTSK (0.62) | CTSKCTSBCTSLCTSS | |
| SCHEMBL6580739 | 0.84 | CTSK (0.56) | CTSKCTSBCTSLCTSS | |
| SCHEMBL6578249 | 0.83 | CTSK (0.58) | CTSKCTSBTAS1R3TAS1R1CTSL | |
| SCHEMBL6582647 | 0.83 | CTSK (0.54) | CTSKCTSBCTSLCTSS | |
| SCHEMBL6580141 | 0.82 | CTSK (0.53) | CTSKCTSBCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180927-A1 | Inhibitors of cysteine protease | SMITHKLINE BEECHAM CORPORATION | 2004-09-16 | — | — | US | claimed |
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |
| US-20020128476-A1 | Inhibitors of cysteine protease | SMITHKLINE BEECHAM CORPORATION | 2002-09-12 | — | — | US | claimed |
| US-20040180927-A1 | Inhibitors of cysteine protease | SMITHKLINE BEECHAM CORPORATION | 2004-09-16 | — | — | US | disclosed |
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | disclosed |
| US-20020128476-A1 | Inhibitors of cysteine protease | SMITHKLINE BEECHAM CORPORATION | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180927-A1 | Inhibitors of cysteine protease | CTSK, CTSZ, CTSS | CTSK 1/4885CTSB 5/4885TAS1R3 3747/4885 |
| US-20020128476-A1 | Inhibitors of cysteine protease | CTRC, RCE1, CTRL | CTSK 100/4885CTSB 60/4885TAS1R3 3402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.