Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.52 |
| ▸ | CTSS | P25774 | 5/20 | 0.41 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | ADAMTS7 | Q9UKP4 | 2/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | ADAMTS1 | Q9UHI8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580363 | 0.91 | CTSK (0.55) | CTSKCTSSCTSLCTSBF10 | |
| SCHEMBL6578319 | 0.91 | CTSK (0.51) | CTSKCTSSCTSLCTSBTP53 | |
| SCHEMBL6584080 | 0.91 | CTSK (0.52) | CTSKCTSSCTSLCTSBCACNA1B | |
| SCHEMBL6578194 | 0.90 | CTSK (0.56) | CTSKCTSSCTSLCTSBCACNA1B | |
| SCHEMBL6581112 | 0.86 | CTSK (0.52) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7429714 | 0.82 | CTSK (0.64) | CTSKCTSSCTSLCTSBCACNA1B | |
| SCHEMBL6404534 | 0.79 | CTSK (0.64) | CTSKCTSSCTSLCTSBCACNA1B | |
| SCHEMBL5098711 | 0.79 | CTSK (0.64) | CTSKCTSSCTSLCTSBCACNA1B | |
| SCHEMBL6578142 | 0.79 | CTSK (0.48) | CTSKCTSSCTSLCTSBPOLB | |
| SCHEMBL6577780 | 0.78 | CTSK (0.55) | CTSKCTSSCTSLCTSBF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |