Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CCR10 | P46092 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580363 | 0.91 | CTSK (0.55) | CTSKCTSLCTSBCTSSF10 | |
| SCHEMBL6578009 | 0.91 | CTSK (0.52) | CTSKCTSLCTSBCTSSF10 | |
| SCHEMBL6578194 | 0.88 | CTSK (0.56) | CTSKCTSLCTSBCTSS | |
| SCHEMBL6582337 | 0.87 | CTSK (0.51) | CTSKCTSLCTSBCTSS | |
| SCHEMBL6584080 | 0.87 | CTSK (0.52) | CTSKCTSLCTSBCTSSF10 | |
| SCHEMBL7429714 | 0.81 | CTSK (0.64) | CTSKCTSLCTSBCTSSPOLB | |
| SCHEMBL6404534 | 0.78 | CTSK (0.64) | CTSKCTSLCTSBCTSSPOLB | |
| SCHEMBL5098711 | 0.78 | CTSK (0.64) | CTSKCTSLCTSBCTSSPOLB | |
| SCHEMBL6577780 | 0.78 | CTSK (0.55) | CTSKCTSLCTSBCTSSF10 | |
| SCHEMBL6578142 | 0.78 | CTSK (0.48) | CTSKCTSLCTSBCTSSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |