Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | F2 | P00734 | 6/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 9/20 | 0.41 |
| ▸ | PLAU | P00749 | 5/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.40 |
| ▸ | PLG | P00747 | 3/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578319 | 0.91 | CTSK (0.51) | CTSKF2CTSLCTSBCTSS | |
| SCHEMBL6578009 | 0.91 | CTSK (0.52) | CTSKCTSLCTSBCTSSF10 | |
| SCHEMBL6578194 | 0.89 | CTSK (0.56) | CTSKCTSLCTSBCTSS | |
| SCHEMBL6584080 | 0.87 | CTSK (0.52) | CTSKF2CTSLCTSBCTSS | |
| SCHEMBL6577780 | 0.87 | CTSK (0.55) | CTSKF2CTSLCTSBCTSS | |
| SCHEMBL7429714 | 0.82 | CTSK (0.64) | CTSKCTSLCTSBCTSS | |
| SCHEMBL6404534 | 0.79 | CTSK (0.64) | CTSKCTSLCTSBCTSS | |
| SCHEMBL5098711 | 0.79 | CTSK (0.64) | CTSKCTSLCTSBCTSS | |
| SCHEMBL6578142 | 0.79 | CTSK (0.48) | CTSKCTSLCTSBCTSS | |
| SCHEMBL6580239 | 0.78 | KMT2A (0.49) | CTSKF2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |