Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 7/20 | 0.60 |
| ▸ | KCNJ3 | P48549 | 7/20 | 0.60 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | PRKX | P51817 | 1/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.53 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.53 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 6/20 | 0.52 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.51 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20258417 | 0.82 | P2RX4 (0.67) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL6580500 | 0.81 | EPHX2 (0.57) | ALDH1A1LMNAPOLBKDM4EMEN1 | |
| SCHEMBL6577319 | 0.79 | NLRP3 (0.59) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL18301640 | 0.79 | P2RX4 (0.72) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL6577874 | 0.79 | MEN1 (0.61) | ALDH1A1ANO1P2RX4KDM4EMEN1 | |
| SCHEMBL19576469 | 0.78 | ALDH1A1 (0.77) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL6580223 | 0.76 | POLB (0.54) | ALDH1A1POLBPRKXCLK4KDM4E | |
| SCHEMBL6579874 | 0.75 | KDM4E (0.52) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL32664293 | 0.75 | KCNJ5 (0.61) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL13602309 | 0.75 | KMT2A (0.64) | ALDH1A1LMNAPOLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |