Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 4/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577234 | 0.74 | LOXL2 (0.53) | CA2LOXL2KDR | |
| SCHEMBL6577433 | 0.72 | HTR1A (0.41) | AURKAAURKBKDM4E | |
| SCHEMBL2241498 | 0.71 | CYP1A2 (0.44) | CA2KDM4ERAB9ASORT1NPC1 | |
| SCHEMBL823222 | 0.71 | CYP1A2 (0.44) | CA2KDM4ERAB9ASORT1NPC1 | |
| SCHEMBL30131399 | 0.69 | CA2 (0.40) | CA2RAB9ANPC1 | |
| SCHEMBL12742983 | 0.67 | GRM4 (0.41) | PSMD14KDM4ESLC40A1 | |
| SCHEMBL1284802 | 0.66 | CA2 (0.51) | CA2KDM4ERAB9ASORT1NPC1 | |
| SCHEMBL7693873 | 0.65 | LOXL2 (0.43) | LOXL2L3MBTL1AURKALCKMET | |
| SCHEMBL1088793 | 0.64 | KDM4E (0.67) | PSMD14L3MBTL1KDM4ERAB9AKDM4A | |
| SCHEMBL6579639 | 0.64 | KDM4E (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1199556-B1 | Optical sensor for measuring an analyte and method of manufacturing the same | METTLER TOLEDO GMBH (CH) | 2004-05-06 | — | — | EP | claimed |
| US-6653148-B2 | Optical sensor for determining an analyte, and method of manufacturing the optical sensor | METTLER-TOLEDO GMBH (CH) | 2003-11-25 | — | — | US | claimed |
| US-20030017078-A1 | Sensor matrix that is made up substantially of a fluoropolymer containing luminescent indicator with a metal complex of ruthenium, rhenium, rhodium or iridium, and with at least one at least partially fluorinated ligand. | METTLER-TOLEDO GMBH (CH) | 2003-01-23 | — | — | US | claimed |
| EP-1199556-A1 | Optical sensor for measuring an analyte and method of manufacturing the same | Mettler-Toledo GmbH (CH) | 2002-04-24 | — | — | EP | claimed |
| EP-1199556-B1 | Optical sensor for measuring an analyte and method of manufacturing the same | METTLER TOLEDO GMBH (CH) | 2004-05-06 | — | — | EP | disclosed |
| US-6653148-B2 | Optical sensor for determining an analyte, and method of manufacturing the optical sensor | METTLER-TOLEDO GMBH (CH) | 2003-11-25 | — | — | US | disclosed |
| US-20030017078-A1 | Sensor matrix that is made up substantially of a fluoropolymer containing luminescent indicator with a metal complex of ruthenium, rhenium, rhodium or iridium, and with at least one at least partially fluorinated ligand. | METTLER-TOLEDO GMBH (CH) | 2003-01-23 | — | — | US | disclosed |
| EP-1199556-A1 | Optical sensor for measuring an analyte and method of manufacturing the same | Mettler-Toledo GmbH (CH) | 2002-04-24 | — | — | EP | disclosed |