Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582239 | 0.92 | GAA (0.32) | — | |
| SCHEMBL6585914 | 0.84 | TRPM8 (0.30) | — | |
| SCHEMBL987844 | 0.78 | PARP1 (0.39) | BRD4SMN1; SMN2KDM4ETSHRHSD17B10 | |
| SCHEMBL987842 | 0.78 | PARP1 (0.39) | BRD4SMN1; SMN2KDM4ETSHRHSD17B10 | |
| SCHEMBL6949037 | 0.78 | KDM4E (0.35) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6949031 | 0.78 | KDM4E (0.35) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6582588 | 0.77 | ELANE (0.30) | — | |
| SCHEMBL6583200 | 0.77 | POLB (0.39) | NPC1RAB9ASMN1; SMN2ATMALDH1A1 | |
| SCHEMBL13254983 | 0.76 | DHFR (0.38) | — | |
| SCHEMBL6950342 | 0.75 | KMT2A (0.37) | SMN1; SMN2KDM4EHSD17B10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155012-B1 | ANTI-CANCER DIHYDROQUINAZOLINE DERIVATIVES | CANCER REC TECH LTD (GB) | 2004-04-14 | — | — | EP | disclosed |
| US-6699861-B1 | ANTI-CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2004-03-02 | — | — | US | disclosed |