Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 5/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.57 |
| ▸ | DRD3 | P35462 | 3/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577731 | 0.86 | ADRA1B (0.76) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL21802161 | 0.84 | DRD2 (0.66) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL22125572 | 0.81 | ADRA1B (0.73) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL21802151 | 0.80 | DRD2 (0.70) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL2315895 | 0.80 | ADRA1D (0.73) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL2510367 | 0.80 | ADRA1D (0.73) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9987656 | 0.79 | ADRA1D (0.72) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL12223771 | 0.78 | DRD3 (0.68) | DRD2DRD3 | |
| SCHEMBL21802088 | 0.78 | DRD2 (0.83) | ADRA1BADRA1DADRA1ADRD2DRD3 | |
| SCHEMBL9026888 | 0.78 | DRD2 (0.79) | ADRA1BADRA1DADRA1ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200406-B1 | CYCLIC AMIDES AND IMIDES HAVING SELECTIVE ANTAGONIST ACTIVITY AT ALPHA-1D ADRENERGIC RECEPTOR | RECORDATI CHEM PHARM (IT) | 2004-11-24 | — | — | EP | disclosed |