SCHEMBL6580265

SCHEMBL6580265

CCc1ccc(C(=O)c2cccc(C(=O)C(N)O)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 1/20 0.42
CNR2 P34972 2/20 0.42
CNR1 P21554 1/20 0.42
PTGS2 P35354 4/20 0.39
PTGS1 P23219 3/20 0.39
PLK1 P53350 1/20 0.39
PBRM1 Q86U86 1/20 0.39
LTC4S Q16873 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259581 0.86 L3MBTL1 (0.59) L3MBTL1ATMTDP1MAPTHTT
SCHEMBL6579956 0.82 LMNA (0.58) L3MBTL1ATMMAPTHTTSMN1; SMN2
SCHEMBL25142152 0.80 L3MBTL1 (0.52) L3MBTL1ATMTDP1MAPTHTT
SCHEMBL5673080 0.79 CNR2 (0.56) L3MBTL1ATMTDP1MAPTHTT
SCHEMBL9854092 0.78 L3MBTL1 (0.50) L3MBTL1ATMTDP1MAPTHTT
SCHEMBL11865541 0.78 PBRM1 (0.66) L3MBTL1ATMTDP1MAPTHTT
SCHEMBL8074583 0.75 ALDH1A1 (0.52) L3MBTL1ATMTDP1MAPTHTT
SCHEMBL975055 0.75 ALDH1A1 (0.65) L3MBTL1ATMTDP1MAPTHTT
SCHEMBL2935942 0.75 ALDH1A1 (0.70) TDP1MAPTHTTSMN1; SMN2ALDH1A1
Ammonia Solution, Strong SCHEMBL8465674 0.73 ALDH1A1 (0.63) L3MBTL1ATMTDP1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0716088-B1 PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS SUMITOMO CHEMICAL CO (JP) 2004-02-18 EP disclosed
EP-0716088-A1 PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-12 EP disclosed