Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259581 | 0.91 | L3MBTL1 (0.59) | L3MBTL1ATMTDP1CNR2MAPT | |
| SCHEMBL25142152 | 0.85 | L3MBTL1 (0.52) | L3MBTL1ATMTDP1CNR2MAPT | |
| SCHEMBL5673080 | 0.84 | CNR2 (0.56) | L3MBTL1ATMTDP1CNR2MAPT | |
| SCHEMBL11596560 | 0.84 | ATM (0.64) | L3MBTL1ATMTDP1ALDH1A1NPC1 | |
| SCHEMBL10624502 | 0.82 | ATM (0.67) | L3MBTL1ATMTDP1ALDH1A1NPC1 | |
| SCHEMBL4349236 | 0.82 | ATM (0.65) | L3MBTL1ATMTDP1MAPTSMN1; SMN2 | |
| SCHEMBL9854110 | 0.81 | LMNA (0.59) | L3MBTL1ATMTDP1CNR2MAPT | |
| SCHEMBL3890873 | 0.80 | CNR2 (0.51) | CNR2MAPTSMN1; SMN2ALDH1A1PTGS2 | |
| SCHEMBL8074583 | 0.80 | ALDH1A1 (0.52) | L3MBTL1ATMTDP1CNR2MAPT | |
| SCHEMBL11865541 | 0.80 | PBRM1 (0.66) | L3MBTL1ATMTDP1CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |