Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579797 | 0.82 | MAPK1 (0.38) | MAPK1HCAR3NPC1HSD17B10ERCC5 | |
| SCHEMBL6948864 | 0.80 | NPC1 (0.48) | MAPK1HCAR3NPC1ALDH1A1MEN1 | |
| SCHEMBL8921457 | 0.78 | MAPK1 (0.53) | MAPK1NPC1HSD17B10ALDH1A1LMNA | |
| SCHEMBL9111798 | 0.75 | HCAR3 (0.46) | HCAR3HTT | |
| SCHEMBL8925425 | 0.73 | GHSR (0.41) | MAPK1HSD17B10ERCC5FEN1MEN1 | |
| SCHEMBL4142949 | 0.72 | ALDH1A1 (0.47) | MAPK1NPC1HSD17B10KDM4CALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL9386542 | 0.71 | NPC1 (0.45) | MAPK1HCAR3NPC1ALDH1A1MEN1 | |
| SCHEMBL22975616 | 0.70 | MAPK1 (0.41) | MAPK1ALDH1A1LMNA | |
| SCHEMBL20128067 | 0.70 | MAPK1 (0.33) | MAPK1NPC1ALDH1A1 | |
| SCHEMBL6582834 | 0.70 | MAPK1 (0.44) | MAPK1NPC1HSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |