Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921457 | 0.84 | MAPK1 (0.53) | TSHRHSD17B10KAT2BHSD11B1MAPT | |
| SCHEMBL6579797 | 0.76 | MAPK1 (0.38) | TSHRHPGDHSD17B10HSD11B1MAPK1 | |
| SCHEMBL8923655 | 0.74 | FLT1 (0.35) | TSHRHPGDHSD11B1MAPK1KMT2A | |
| SCHEMBL6580324 | 0.73 | MAPK1 (0.42) | HSD17B10MAPK1MEN1KMT2AERCC5 | |
| SCHEMBL6948864 | 0.73 | NPC1 (0.48) | TP53MAPTMAPK1MEN1KMT2A | |
| SCHEMBL9111798 | 0.72 | HCAR3 (0.46) | HPGD | |
| SCHEMBL8924130 | 0.72 | HCAR3 (0.46) | HPGD | |
| SCHEMBL6947622 | 0.71 | NAALAD2 (0.45) | GHSRHSD11B1GAATP53MAPT | |
| SCHEMBL10971190 | 0.71 | MAPK1 (0.51) | GHSRTSHRHPGDHSD17B10KAT2B | |
| SCHEMBL10975490 | 0.70 | MAPK1 (0.50) | GHSRTSHRKAT2BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |