Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 2/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580558 | 0.85 | SLC22A12 (0.42) | BRS3SLC29A1AURKACSNK1EGSK3A | |
| SCHEMBL8325612 | 0.84 | LMNA (0.43) | BRS3SLC29A1AURKACSNK1EGSK3A | |
| SCHEMBL8433819 | 0.83 | BRS3 (0.43) | BRS3AURKACSNK1EGSK3AGSK3B | |
| SCHEMBL6580022 | 0.83 | BRS3 (0.43) | BRS3AURKACSNK1EGSK3AGSK3B | |
| SCHEMBL6580124 | 0.79 | MEN1 (0.41) | BRS3AURKACSNK1EGSK3AGSK3B | |
| SCHEMBL6580054 | 0.78 | BRS3 (0.39) | BRS3AURKACSNK1EGSK3AGSK3B | |
| SCHEMBL8792168 | 0.78 | EDNRA (0.41) | BRS3SLC29A1AURKACSNK1EGSK3A | |
| SCHEMBL8785847 | 0.78 | BRS3 (0.42) | BRS3AURKACSNK1EGSK3AGSK3B | |
| SCHEMBL3839001 | 0.77 | EDNRA (0.45) | BRS3AURKACSNK1EGSK3AGSK3B | |
| SCHEMBL7501699 | 0.74 | LMNA (0.38) | BRS3AURKACSNK1EGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804435-B1 | NOVEL IMIDAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2004-03-10 | — | — | EP | disclosed |
| US-5856509-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1999-01-05 | — | — | US | disclosed |