Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580558 | 0.92 | SLC22A12 (0.42) | LMNABRS3SLC29A1SLC22A12SMN1; SMN2 | |
| SCHEMBL6580573 | 0.84 | BRS3 (0.42) | LMNABRS3SLC29A1SLC22A12SMN1; SMN2 | |
| SCHEMBL8434942 | 0.83 | BRS3 (0.42) | LMNABRS3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8792168 | 0.83 | EDNRA (0.41) | LMNABRS3SLC29A1AURKACSNK1E | |
| SCHEMBL8431736 | 0.83 | BRS3 (0.42) | LMNABRS3SLC22A12SMN1; SMN2AURKA | |
| SCHEMBL8330624 | 0.80 | EDNRB (0.40) | LMNABRS3POLBTP53 | |
| SCHEMBL8323946 | 0.79 | EDNRB (0.40) | LMNABRS3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7501396 | 0.78 | EDNRA (0.45) | LMNABRS3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8434873 | 0.78 | EDNRA (0.45) | BRS3SLC22A12SMN1; SMN2AURKACSNK1E | |
| SCHEMBL7501699 | 0.78 | LMNA (0.38) | LMNABRS3SLC22A12SMN1; SMN2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856509-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1999-01-05 | — | — | US | disclosed |