Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | FNTA | P49354 | 3/20 | 0.51 |
| ▸ | FNTB | P49356 | 3/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.47 |
| ▸ | ITGAV | P06756 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581023 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MAPTHTTFNTAFNTB | |
| SCHEMBL6581305 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MAPTHTTFNTAFNTB | |
| SCHEMBL6578974 | 0.93 | ALDH1A1 (0.60) | ALDH1A1MAPTHTTFNTAFNTB | |
| SCHEMBL658678 | 0.87 | FNTA (0.50) | ALDH1A1MAPTHTTFNTAFNTB | |
| SCHEMBL660764 | 0.86 | FNTA (0.54) | MAPTFNTAFNTBITGB3ITGAV | |
| SCHEMBL18110925 | 0.85 | HTT (0.56) | ALDH1A1MAPTHTTFFAR1LMNA | |
| SCHEMBL12268202 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MAPTFNTAFNTBGAA | |
| SCHEMBL1811811 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MAPTFNTAFNTBGAA | |
| Hydrochloric Acid SCHEMBL7334847 | 0.84 | FNTA (0.52) | MAPTFNTAFNTBITGB3ITGAV | |
| SCHEMBL12268213 | 0.84 | GABBR2 (0.61) | ALDH1A1MAPTFNTAFNTBITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113564144-B | Lipase mutant and application thereof | 上海奥博生物医药股份有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-118956817-A | Lipase mutant and application thereof | 上海奥博生物医药股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-113564144-A | Lipase mutant and application thereof | 上海奥博生物医药技术有限公司 | 2021-10-29 | — | — | CN | disclosed |
| EP-0986389-B1 | NOVEL PROCESS | SMITHKLINE BEECHAM CORP (US) | 2004-10-13 | — | — | EP | disclosed |
| US-20040147754-A1 | Novel process | SMITHKLINE BEECHAM PLC | 2004-07-29 | — | — | US | disclosed |
| US-6716985-B2 | ALCOHOLISM, PSYCHOLOGICAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2004-04-06 | — | — | US | disclosed |
| US-6489347-B1 | NOVEL INTERMEDIATE CARBOXALDEHYDES FOR PHARMACEUTICAL PRODUCTS WITH ANTIDEPRESSANT AND ANTI-PARKINSON PROPERTIES | SMITHKLINE BEECHAM PLC (GB) | 2002-12-03 | — | — | US | disclosed |
| US-20020133011-A1 | Novel process | SMITHKLINE BEECHAM PLC | 2002-09-19 | — | — | US | disclosed |
| EP-0986389-A4 | NOVEL PROCESS | SMITHKLINE BEECHAM CORP (US) | 2001-09-12 | — | — | EP | disclosed |
| EP-0986389-A1 | NOVEL PROCESS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998053824-A1 | NOVEL PROCESS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020133011-A1 | Novel process | HTR1A, HTR4, MAOA | ALDH1A1 900/4885MAPT 1827/4885HTT 941/4885 |
| US-20040147754-A1 | Novel process | HTR1A, HTR4, HTR2B | ALDH1A1 1013/4885MAPT 2512/4885HTT 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.