Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 12/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582688 | 0.90 | CYP2D6 (0.44) | SCDTGFBR1ADRA1AADRA1BCYP2D6 | |
| SCHEMBL6582672 | 0.76 | GRIN2B (0.39) | SCDADRA1AADRA1BCYP2D6CYP2C9 | |
| SCHEMBL6581653 | 0.75 | HTR1A (0.37) | — | |
| Hydrochloric Acid SCHEMBL6582680 | 0.75 | F10 (0.45) | SCDCYP2D6CYP2C9GRIN2BSLC2A1 | |
| SCHEMBL6584670 | 0.74 | HTR1A (0.37) | — | |
| SCHEMBL5867949 | 0.73 | MEN1 (0.38) | ADRA1AADRA1BCYP2D6KDM4EPKM | |
| SCHEMBL6583196 | 0.71 | BRD4 (0.38) | SCDTGFBR1ADRA1AADRA1BGRIN2B | |
| Hydrochloric Acid SCHEMBL6582721 | 0.71 | F10 (0.40) | SCDCYP2C9GRIN2BSLC2A1KDM4E | |
| SCHEMBL6582799 | 0.71 | CCNT1 (0.38) | SCDTGFBR1CYP2D6CYP2C9GRIN2B | |
| SCHEMBL6582859 | 0.70 | GRIN2B (0.46) | SCDCYP2D6CYP2C9GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455788-A1 | 1-GLYCINYL-4-AMINOMETHYL-PIPERIDINE DERIVATIVES AS FACTOR XA INHIBITORS | ELI LILLY AND COMPANY (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003049737-A1 | CHEMICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |