Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584387 | 0.86 | CASP1 (0.57) | CASP1HSD17B10L3MBTL1PDE4BCYP3A4 | |
| SCHEMBL6582968 | 0.82 | CASP1 (0.45) | CASP1HSD17B10L3MBTL1PDE4BPDE4A | |
| SCHEMBL6584961 | 0.80 | PDE4B (0.44) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| SCHEMBL6582613 | 0.78 | SIGMAR1 (0.49) | — | |
| SCHEMBL6587626 | 0.75 | PDE4B (0.48) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| SCHEMBL6585141 | 0.72 | PDE4B (0.47) | CASP1HSD17B10L3MBTL1PDE4BPDE4A | |
| SCHEMBL6588285 | 0.71 | HIF1A (0.45) | L3MBTL1PDE4BCYP3A4ALDH1A1GAA | |
| SCHEMBL15489211 | 0.70 | MAOB (0.50) | PDE4BALDH1A1GAAPDE4APDE4C | |
| SCHEMBL6584657 | 0.68 | ALDH1A1 (0.60) | PDE4BCYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL20969213 | 0.68 | ACHE (0.61) | L3MBTL1PDE4BCYP3A4ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |