Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584387 | 0.86 | CASP1 (0.57) | CASP1HSD17B10L3MBTL1PDE4BPDE4A | |
| SCHEMBL6582613 | 0.83 | SIGMAR1 (0.49) | — | |
| SCHEMBL6585217 | 0.82 | CASP1 (0.45) | CASP1HSD17B10L3MBTL1PDE4BPDE4A | |
| SCHEMBL6584961 | 0.80 | PDE4B (0.44) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| SCHEMBL8004519 | 0.76 | HSD17B10 (0.43) | CASP1HSD17B10SMPD1ESR1PDE4B | |
| SCHEMBL7767598 | 0.76 | HSD17B10 (0.43) | CASP1HSD17B10SMPD1ESR1PDE4B | |
| SCHEMBL6587626 | 0.75 | PDE4B (0.48) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| SCHEMBL8229686 | 0.75 | HSD17B10 (0.43) | CASP1HSD17B10SMPD1L3MBTL1PDE4B | |
| Ammonia Solution, Strong SCHEMBL8004523 | 0.74 | PDE4B (0.42) | CASP1HSD17B10SMPD1L3MBTL1PDE4B | |
| SCHEMBL8354813 | 0.72 | PDE4A (0.49) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |