Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588483 | 0.86 | NPY5R (0.47) | MC4RMC3RKMT2AALOX5NPY5R | |
| SCHEMBL6585427 | 0.84 | NPY5R (0.42) | KMT2ANPY5RSIGMAR1ADRA1ARIOK2 | |
| SCHEMBL6584761 | 0.82 | RIOK2 (0.38) | NPY5RBCHEHTR2CADRA1AHTR2B | |
| SCHEMBL6584448 | 0.82 | NPY5R (0.52) | KMT2ANPY5RNPC1MAPTRAB9A | |
| SCHEMBL6588259 | 0.78 | RIOK2 (0.38) | MC4RMC3RKMT2AALOX5NPY5R | |
| SCHEMBL6585290 | 0.78 | RIOK2 (0.36) | MC4RMC3RKMT2AALOX5MAPT | |
| SCHEMBL6589152 | 0.76 | RIOK2 (0.40) | MC4RMC3RKMT2ANPC1RAB9A | |
| SCHEMBL6585559 | 0.76 | LMNA (0.44) | KMT2ANPC1ALDH1A1GAAMAPT | |
| SCHEMBL6584847 | 0.67 | NPY5R (0.76) | NPY5RRIOK2MAPK8GSK3AMAPK10 | |
| SCHEMBL6584786 | 0.65 | PTGS2 (0.43) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | claimed |