Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585131 | 0.83 | MTNR1A (0.46) | MAPTMEN1KMT2ABACE1ALDH1A1 | |
| SCHEMBL6584448 | 0.79 | NPY5R (0.52) | LMNACYP1A2NPC1RAB9AKDM4E | |
| SCHEMBL6588483 | 0.77 | NPY5R (0.47) | CYP1A2KDM4ESLC6A3MEN1KMT2A | |
| SCHEMBL6583451 | 0.76 | MC4R (0.37) | NPC1RAB9AMAPTSLC6A3KMT2A | |
| SCHEMBL6587116 | 0.76 | NPC1 (0.37) | LMNASMN1; SMN2CYP1A2NPC1RAB9A | |
| SCHEMBL6584786 | 0.76 | PTGS2 (0.43) | LMNACYP1A2MAPTUTS2R | |
| SCHEMBL6585427 | 0.75 | NPY5R (0.42) | LMNACYP1A2KDM4ECYP3A4MEN1 | |
| SCHEMBL6584761 | 0.73 | RIOK2 (0.38) | SLC6A3BACE1GSK3AMAPK10RIOK2 | |
| SCHEMBL28658857 | 0.71 | NPC1 (0.70) | LMNASMN1; SMN2CYP1A2NPC1RAB9A | |
| SCHEMBL6588259 | 0.69 | RIOK2 (0.38) | SMN1; SMN2SLC6A3MEN1KMT2ARIOK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | claimed |