Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585427 | 0.90 | NPY5R (0.42) | NPY5RMEN1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL6588483 | 0.82 | NPY5R (0.47) | NPY5RMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL6583451 | 0.82 | MC4R (0.37) | NPY5RKMT2AADRA1ANPC1RAB9A | |
| SCHEMBL6584761 | 0.81 | RIOK2 (0.38) | NPY5RADRA1AGSK3AMAPK10RIOK2 | |
| SCHEMBL6585559 | 0.79 | LMNA (0.44) | MEN1KMT2ACYP3A4CYP1A2KDM4E | |
| SCHEMBL6588259 | 0.77 | RIOK2 (0.38) | NPY5RMEN1KMT2AADRA1ACASP3 | |
| SCHEMBL6585290 | 0.76 | RIOK2 (0.36) | MEN1KMT2AKDM4EADRA1AMAPT | |
| SCHEMBL6589152 | 0.75 | RIOK2 (0.40) | MEN1KMT2AADRA1ANPC1RAB9A | |
| SCHEMBL6583477 | 0.71 | EPHX1 (0.45) | LMNACYP2C9 | |
| SCHEMBL6587116 | 0.69 | NPC1 (0.37) | CYP1A2KDM4ELMNANPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | claimed |