Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 5/20 | 0.40 |
| ▸ | GSK3A | P49840 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.40 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TPH1 | P17752 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585290 | 0.83 | RIOK2 (0.36) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL6584761 | 0.82 | RIOK2 (0.38) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL6585949 | 0.77 | RIOK2 (0.39) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL6588483 | 0.77 | NPY5R (0.47) | RIOK2GSK3AMAPK10KMT2AMC4R | |
| SCHEMBL6583451 | 0.76 | MC4R (0.37) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL6588259 | 0.76 | RIOK2 (0.38) | RIOK2KMT2AMC4RMC3RMEN1 | |
| SCHEMBL6584448 | 0.75 | NPY5R (0.52) | RIOK2GSK3AMAPK10NPC1RAB9A | |
| SCHEMBL6585427 | 0.71 | NPY5R (0.42) | RIOK2GSK3AMAPK10KMT2AMEN1 | |
| SCHEMBL6585559 | 0.67 | LMNA (0.44) | RIOK2GSK3AMAPK10NPC1RAB9A | |
| SCHEMBL6584957 | 0.67 | NPY5R (0.62) | RIOK2GSK3AMAPK10MAPK8HIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | claimed |