Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.41 |
| ▸ | TPH1 | P17752 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584448 | 0.71 | NPY5R (0.52) | LMNACYP2C9 | |
| SCHEMBL6584786 | 0.71 | PTGS2 (0.43) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL6583482 | 0.69 | EPHX1 (0.43) | EPHX1CXCR1CXCR2TPH1FAAH | |
| SCHEMBL6585213 | 0.69 | NPY5R (0.55) | CXCR1CXCR2FAAHLMNACHRM1 | |
| SCHEMBL3152241 | 0.66 | EPHX1 (1.00) | EPHX1CXCR1CXCR2FAAHPTGS1 | |
| SCHEMBL260688 | 0.66 | EPHX1 (1.00) | EPHX1CXCR1CXCR2FAAHPTGS1 | |
| SCHEMBL1883571 | 0.66 | EPHX1 (1.00) | EPHX1CXCR1CXCR2FAAHPTGS1 | |
| Hydrochloric Acid SCHEMBL3424822 | 0.65 | EPHX1 (0.96) | EPHX1CXCR1CXCR2FAAHPTGS1 | |
| SCHEMBL11570387 | 0.63 | PTGS2 (0.56) | EPHX1CXCR1CXCR2FAAHPTGS1 | |
| SCHEMBL5080304 | 0.63 | PTGS2 (0.56) | EPHX1CXCR1CXCR2FAAHPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | claimed |